Detalhe da pesquisa
1.
Reducing acetylated tau is neuroprotective in brain injury.
Cell
; 184(10): 2715-2732.e23, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852912
2.
Quantitative trait locus (xQTL) approaches identify risk genes and drug targets from human non-coding genomes.
Hum Mol Genet
; 31(R1): R105-R113, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36018824
3.
Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug repurposing in Alzheimer's disease.
Genome Res
; 31(10): 1900-1912, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627474
4.
Peripheral sTREM2-Related Inflammatory Activity Alterations in Early-Stage Alzheimer's Disease.
J Immunol
; 208(10): 2283-2299, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35523454
5.
Microglial immunometabolism endophenotypes contribute to sex difference in Alzheimer's disease.
Alzheimers Dement
; 20(2): 1334-1349, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37985399
6.
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis.
J Lipid Res
; 64(4): 100349, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36806709
7.
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19.
PLoS Biol
; 18(11): e3000970, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33156843
8.
Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer's disease.
PLoS Comput Biol
; 18(7): e1010287, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849618
9.
Population-based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans.
Alzheimers Dement
; 19(5): 1876-1887, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36331056
10.
KRAS Activating Signaling Triggers Arteriovenous Malformations.
Trends Biochem Sci
; 43(7): 481-483, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748115
11.
Pharmacogenomics for immunotherapy and immune-related cardiotoxicity.
Hum Mol Genet
; 29(R2): R186-R196, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32620943
12.
Pharmacogenomics meets precision cardio-oncology: is there synergistic potential?
Hum Mol Genet
; 29(R2): R177-R185, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32601683
13.
Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer.
Am J Hum Genet
; 104(5): 861-878, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006514
14.
A network-based deep learning methodology for stratification of tumor mutations.
Bioinformatics
; 37(1): 82-88, 2021 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33416857
15.
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.
Pharmacol Rev
; 71(1): 1-19, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30545954
16.
Cardiac risk stratification in cancer patients: A longitudinal patient-patient network analysis.
PLoS Med
; 18(8): e1003736, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34339408
17.
Network-based prediction of drug-target interactions using an arbitrary-order proximity embedded deep forest.
Bioinformatics
; 36(9): 2805-2812, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31971579
18.
iDrug: Integration of drug repositioning and drug-target prediction via cross-network embedding.
PLoS Comput Biol
; 16(7): e1008040, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32667925
19.
Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.
PLoS Comput Biol
; 16(2): e1007701, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101536
20.
Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects.
Brain
; 143(7): 2106-2118, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32568404